Plasmid Replicon Diversity of Clinical Uropathogenic Escherichia coli Isolates from Riyadh, Saudi Arabia

The aim of this study was to identify and compare the plasmid replicons clinical uropathogenic Escherichia coli (UPEC) isolates, involving extended spectrum β-lactamase (ESBL)-positive ESBL-negative, E. ST131 non-ST131 various subclones. Plasmid replicon typing on 24 UPEC isolates carried out using polymerase chain reaction-based typing. A statistical analysis performed assess associations between types ESBL carriage, evaluate link high carriage. Eight replicons, I1α, N2, Iγ, X1, FIIS, K, FIA, FII were detected. most common identified here. ESBL-positive highly associated with FIIS while FIA present only in ESBL-negative group. I1α N2 compared non-ST131. No found carriage number or type ESBLs isolates. diversity observed patterns our indicates that they might be originated from different sources. presence reported previously animal sources suggests a possible transfer antimicrobial resistance human bacterial